bromocriptine (Parlodel, Cycloset)

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Introduction

Tradename: Parlodel.

Indications

Contraindications

Caution:

  • avoid alcohol
  • avoid exposure to cold

pregnancy category = -

safety in lactation = -

Dosage

  • start 1.25 mg PO BID with meals
  • max 40 mg/day
  • take with milk or food

Tabs: 2.5 & 5 mg, 0.8 mg (Cycloset)

Pharmacokinetics

elimination via liver

1/2life = 4-4.5 hours

1/2life = 45-50 hours

Adverse effects

# common with initiation of therapy

* most common side effect (68%)

Drug interactions

Mechanism of action

More general terms

Additional terms

References

  1. Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1990
  2. The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
  3. Saunders Manual of Medical Practice, Rakel (ed), WB Saunders, Philadelphia, 1996, pg 1051
  4. Drug Information & Medication Formulary, Veterans Affairs, Central California Health Care System, 1st ed., Ravnan et al eds, 1998
  5. Kaiser Permanente Northern California Regional Drug Formulary, 1998
  6. Prescriber's Letter 18(2): 2011 COMMENTARY: Cycloset: A New Bromocriptine Formulation for Diabetes CHART: Drug Classes for Type 2 Diabetes Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=270205&pb=PRL (subscription needed) http://www.prescribersletter.com
  7. 7.0 7.1 Deprecated Reference

Database