striatum
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Structure
* image[3]
Afferents
- cortical afferents
- medium-sized spiny neurons in dorsal striatum receive projections from the neocortex*
- most afferents from pyramidal neurons in layer 5
- also neurons in layers 3 & 4
- ventral striatum receives projections from
- medium-sized spiny neurons in dorsal striatum receive projections from the neocortex*
- subcortical afferents
- dopaminergic fibers
- largely ipsilateral from
- topographically clustered
- anterolateral cells of the pars compacta project to the head of the caudate
- caudomedial cells project to the putamen
- anteromedial cells in the pars compacta & ventral tegmental area project to the ventral striatum
- ipsilateral dorsal raphe (serotoninergic & other)
- bilateral fibers from the reticular formation
- caudal region of spinal trigeminal nucleus
- central gray area
- posterior & lateral hypothalamus
- histamine, GABA, galanin, met-enkephalin within same neuron
- alpha-MSH
- thalamus
- subthalamic nucleus
- globus pallidus
- dopaminergic fibers
* schematic: Connections of the Basal Nuclei[4]
Efferents
- three major striatal efferent targets
- external globus pallidus
- each segment of the globus pallidus receives afferents from a column of overlying striatum
- internal globus pallidus, including substantia nigra pars reticulata
- substantia nigra pars compacta
- external globus pallidus
* medium-sized spiny neurons in dorsal striatum receiving projections from the neocortex also contribute to striatal efferents
More general terms
Component of
Components
References
- ↑ The Human Nervous System, George Paxinos, Academic Press, San Diego CA 1990
- ↑ The Human Nervous System, an atomical viewpoint, Barr ML, 2nd ed, Harper & Row, Hargerstown, MD, 1974
- ↑ 3.0 3.1 lumen Anatomy & Physiology. Module 12. The Nervous System The Central Nervous System Frontal section of the Cerebral Cortex and Basal Nuclei https://courses.lumenlearning.com/austincc-ap1/chapter/the-central-nervous-system/#m46533-fig-ch13_02_04
- ↑ 4.0 4.1 lumen Anatomy & Physiology. Module 12. The Nervous System The Central Nervous System Connections of the Basal Nuclei https://courses.lumenlearning.com/austincc-ap1/chapter/the-central-nervous-system/#m46533-fig-ch13_02_05