1st pass metabolism

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[1][2]

Introduction

Intestinal uptake & degradation within the intestine, liver or portal circulation before a drug or bioagent reaches the systemic circulation. The effect is greater in men than in women[2].

References

  1. ↑ Stedman's Medical Dictionary 27th ed, Williams & Wilkins, Baltimore, 1999
  2. ↑ 2.0 2.1 Geriatrics Review Syllabus, American Geriatrics Society, 5th edition, 2002-2004
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