flurazepam (Dalmane)

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Introduction

Tradename: Dalmane. DEA-controlled substance: class 4.

Indications

short-term management of insomnia

Contraindications

Caution:

  • use with caution in patients receiving other CNS depressants
  • safety in children not yet established

pregnancy category = x

safety in lactation = -

Dosage

15-30 mg PO QHS[1][2]

Tabs: 15, 30 mg.

Pharmacokinetics

elimination via kidney

1/2life = 50-100 hours

protein binding = 96-98 %

elimination by hemodialysis = -

Adverse effects

Drug interactions

Laboratory

Mechanism of action

benzodiazepine

More general terms

More specific terms

References

  1. Jump up to: 1.0 1.1 The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996.
  2. Jump up to: 2.0 2.1 Manual of Medical Therapeutics, 28th ed, Ewald & McKenzie (eds), Little, Brown & Co, Boston, 1995, pg 7
  3. Kaiser Permanente Northern California Regional Drug Formulary, 1998
  4. Clinical Guide to Laboratory Tests, 3rd ed. Teitz ed., W.B. Saunders, 1995

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