flurazepam (Dalmane)

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Introduction

Tradename: Dalmane. DEA-controlled substance: class 4.

Indications

short-term management of insomnia

Contraindications

Caution:

  • use with caution in patients receiving other CNS depressants
  • safety in children not yet established

pregnancy category = x

safety in lactation = -

Dosage

15-30 mg PO QHS[1][2]

Tabs: 15, 30 mg.

Pharmacokinetics

elimination via kidney

1/2life = 50-100 hours

protein binding = 96-98 %

elimination by hemodialysis = -

Adverse effects

Drug interactions

Laboratory

Mechanism of action

benzodiazepine

More general terms

More specific terms

References

  1. 1.0 1.1 The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996.
  2. 2.0 2.1 Manual of Medical Therapeutics, 28th ed, Ewald & McKenzie (eds), Little, Brown & Co, Boston, 1995, pg 7
  3. Kaiser Permanente Northern California Regional Drug Formulary, 1998
  4. Clinical Guide to Laboratory Tests, 3rd ed. Teitz ed., W.B. Saunders, 1995

Database