poly [ADP-ribose] polymerase 1; PARP-1; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; poly[ADP-ribose] synthase 1 (PARP1, ADPRT, PPOL)

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Introduction

also see poly[ADP-ribose]polymerase

Function

Structure

Compartment

nucleus

Notes

  • the ADP-D-ribosyl group of NAD+ is transferred to an acceptor carboxyl group on a histone or the enzyme itself, & further ADP-ribosyl groups are transferred to the 2'-position of the terminal adenosine moiety, building up a polymer with an average chain length of 20-30 units

More general terms

Additional terms

Component of

References

Database