pharmaceutical agents associated with gynecomastia

Introduction

• androgen antagonists
  • cyproterone
  • flutamide
  • finasteride
• antibiotics
  • ethionamide
  • isoniazid
  • ketoconazole
  • metronidazole
• gastrointestinal agents
  • H1 receptor antagonists, cimetidine > ranitidine
  • proton pump inhibitors
  • metoclopramide
• antineoplastic agents
  • alkylating agents
  • methotrexate
  • vinca alkaloids
  • imatinib
• antiarrythmics
  • amiodarone
  • digitoxin
• antihypertensive agents
  • captopril
  • enalopril
  • Ca+2 channel blockers, nifedipine > verapamil > diltiazem
  • alpha methyldopa
  • reserpine
  • spironolactone*
• hormones
  • anabolic steroids
  • estrogens
  • chorionic gonadotropin
  • somatotropin
• mental health agents
  • diazepam
  • haloperidol
  • phenothiazines
  • tricyclic antidepressants
• drugs of abuse
  • ethanol
  • amphetamines
  • heroin
  • marijuana
  • methadone
• miscellaneous
  • auranofin
  • diethylpropion
  • domperidone
  • etretinate
  • phenytoin
  • penicillamine
  • sulindac
  • theophylline

* 100% of patients taking > 100 mg/day

More general terms

• pharmacology