auranofin [gold] (Ridaura)

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Introduction

Tradename: Ridaura. [gold].

Indications

Dosage

Rheumatoid arthritis:

  • starting dose: 3 mg PO QD.
  • 3 mg PO BID or 6 mg QD, max 9 mg QD divided TID
  • discontinue if no response after 3 months on maximum dose

Tabs: 3 mg (29% gold).

Pharmacokinetics

  • therapeutic effects may not be apparent for 3-4 months

elimination via kidney

elimination via feces

1/2life = 26 days

protein binding = 60 %

Monitor

Adverse effects

Use with caution in patients with:

Drug interactions

Mechanism of action

More general terms

Additional terms

References

  1. The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
  2. 2.0 2.1 Drug Information & Medication Formulary, Veterans Affairs, Central California Health Care System, 1st ed., Ravnan et al eds, 1998
  3. Kaiser Permanente Northern California Regional Drug Formulary, 1998
  4. 4.0 4.1 4.2 Deprecated Reference

Database