electronic cigarette; e-cigarette; juul; electronic nicotine delivery system (ENDS)

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Epidemiology

  • < 5% of adults report using e-cigarettes[39]
  • 13%[18] - 20%[3] of adults has tried an electronic cigarette
  • ever use higher among current cigarette smokers (48%) & recent quitters (55%)
  • among high school students, ever-use of e-cigarettes increased from 4.7% to 10.0% from 2011 to 2012[5][13]
  • among adult never smoker of cigarettes, younger adults try e-cigarettes more often than older adults (10% for adults age 18-24 vs 1% for adults age > 45 years of age)[18]
  • 24% of U.S. middle school & high school students report recent exposure to vapors of electronic cigarettes[30]
  • an increase in electronic cigarette use among adult smokers may be associated with an increase in smoking cessation rate[31]
  • may lead youth to start smoking, adults to stop smoking[34]
  • prevalence of nicotine vaping among 12 graders increased 11% to 21% from 2017 to 2018

Indications

Pharmacokinetics

  • peak serum nicotine concentration within 5 minutes, similar to conventional cigarettes[25]

Adverse effects

Complications

Notes

Device:

Products are:

  • marketed & sold to young people
    • FDA regulation prohibits sale of e-cigarettes to persons < 21 years of age [21[
  • readily available online & in shopping malls
  • available in different flavors which may appeal to young people
  • a juul is smaller than a typical e-cigarette
    • looks like a flash drive (see image)[43]
    • its oils come in flavors like mango
    • contains highest nicotine content of any e-cigarette[43]

Contain:

Warnings

  • none
  • do not contain any health warnings comparable to FDA-approved nicotine replacement products or conventional cigarettes
  • two e-liquids sold by HelloCig Electronic Technology Co. Ltd. found to contain tadalafil &/or sildenafil[45]

FDA approval:

  • have not been submitted to the FDA for evaluation or approval
  • FDA has no way of knowing, except for its own limited testing, the levels of nicotine or the amounts or kinds of other chemicals present in the various brands
  • FDA's premarket approval process pass RJ Reynolds Vuse Solo device showing reduced harm compared with traditional tobacco products,

FDA regulation:

  • FDA extends its tobacco authority to e-cigarettes[9][21]
  • FDA threatens to take flavored e-cigarettes of the market[40]
  • FDA will ban sales of flavored e-cigarettes in most retail stores due to popularity & increased use among youths[44]

Most E-cigarettes are made in China

  • quality is inconsistent[8]
  • nicotine intake from e-cigarettes is highly variable[37]

electronic cigarettes are banned on commercial flights[20]

, electronic cigarettes can be used to vaporize cannabis, including marijuana, tetrahydrocannabinol, or hash oil[41]

open-system, refillable devices popular among adolescents[42]

More general terms

More specific terms

Additional terms

References

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  3. 3.0 3.1 CDC Newsroom. Press Release. Feb 28, 2013 Centers for Disease Control and Prevention About one in five U.S. adult cigarette smokers have tried an electronic cigarette. http://www.cdc.gov/media/releases/2013/p0228_electronic_cigarettes.html
  4. Prescriber's Letter 20(5): 2013 Electronic Cigarettes and Hookah Pipes Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=290503&pb=PRL (subscription needed) http://www.prescribersletter.com
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