NF-kappa-B essential modulator; NEMO; NF-kappa-B essential modifier; inhibitor of nuclear factor kappa-B kinase subunit gamma; IkB kinase subunit gamma; I-kappa-B kinase gamma; IKK-gamma; IKKG; IkB kinase-associated protein 1; IKKAP1;FIP-3 (IKBKG, FIP3, NEMO)

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Function

-regulatory subunit of the IKK core complex

Structure

Compartment

cytoplasm. nucleus

Expression

Pathology

More general terms

Component of

References

  1. Rothwarf DM et al IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex. Nature 395:297-300, 1998 PMID: https://www.ncbi.nlm.nih.gov/pubmed/9751060
  2. Yamaoka S et al Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation. Cell 93:1231-40, 1998 PMID: https://www.ncbi.nlm.nih.gov/pubmed/9657155
  3. UniProt http://www.uniprot.org/uniprot/Q9Y6K9.html
  4. IKBKGbase; Note: IKBKG mutation db http://bioinf.uta.fi/IKBKGbase/
  5. GeneReviews https://www.genecards.org/cgi-bin/carddisp.pl?gene=IKBKG

Database