Trpc4-associated protein (short transient receptor potential channel 4-associated protein, Trp4-associated protein, TAP1 protein, TNF-receptor ubiquitous scaffolding/signaling protein, protein TRUSS, TRPC4AP, C20orf188, TRRP4AP)
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Function
- role in activation of NFKB1 in response to ligation of TNFRSF1A
- scaffolding protein to link TNFRSF1A to IKK signalosome
- constitutively associated with TNFRSF1A
- interacts with TRADD, TRAF2, CHUK, IKBKB & IKBKG
Alternative splicing
named isoforms=2