transcription factor E2F4 (E2F-4, E2F4)

From Aaushi
Jump to navigation Jump to search

Function

Structure

Compartment

nucleus

Expression

  • found in all tissue examined including heart, brain, placenta, lung, liver, skeletal muscle, kidney & pancreas
  • present in the growth-arrested state, its abundance does not change significantly as cells move into & through the cell cycle

Polymorphism

  • the poly-Ser region of E2F4 is polymorphic & the number of Ser varies in the population (from 8 to 17)
  • variation might be associated with tumorigenesis

More general terms

References

Database