multivitamin (MVI) with minerals

From Aaushi
Jump to navigation Jump to search

Indications

Contraindications

Clinical trials

[1] small study

Study design

Results:

[2] MAVIS trial

Study design:

Primary outcomes were

Secondary outcomes were related to

Results:

  • after 1 year, none of the measured outcomes differed significantly between the 2 groups

[3] Toronto Study of elderly 85+ years

Results:

[4] Women's Health Initiative

Study design: 161 808 participants, 8 year follow-up

Results:

[5,6] Physicians' Health Study II

Study design

Results:

[10] Iowa Women's Health Study

Study design:

Results:

[16]

[18] COSMOS-Mind

Study design

Results:

More general terms

More specific terms

Additional terms

References

  1. Journal Watch 23(8):66, 2003 Barringer TA et al, Ann Intern Med 138:365, 2003 Fauzi W & Stampfer MI, Ann Intern Med 138:430, 2003 http://www.annals.org/issues/v138n5/full/200303040-00005.html
  2. Avenell A et al Effect of multivitamin and multimineral supplements on morbidity from infections in older people (MAVIS trial): Pragmatic, randomised, double blind, placebo controlled trial. BMJ 2005 Aug 6; 331:324-9. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/16081445 <Internet> http://bmj.bmjjournals.com/cgi/content/full/331/7512/324
  3. Liu BA et al Effect of multivitamin and mineral supplementation on episodes of infection in nursing home residents: a randomized, placebo- controlled study. J Am Geriatr Soc. 2007 Jan;55(1):35-42. PMID: https://www.ncbi.nlm.nih.gov/pubmed/17233683
  4. 4.0 4.1 Neuhouser ML et al. Multivitamin use and risk of cancer and cardiovascular disease in the Women's Health Initiative cohorts. Arch Intern Med 2009 Feb 9; 169:294. PMID: https://www.ncbi.nlm.nih.gov/pubmed/19204221
  5. 5.0 5.1 Gaziano JM et al Multivitamins in the Prevention of Cancer in Men The Physicians' Health Study II Randomized Controlled Trial JAMA. 2012 Nov 14;308(18):1871-80. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/23162860 <Internet> http://jama.jamanetwork.com/article.aspx?articleid=1380451
  6. 6.0 6.1 Sesso HD et al Multivitamins in the Prevention of Cardiovascular Disease in Men. The Physicians' Health Study II Randomized Controlled Trial. JAMA. 2012;308(17):1751-1760 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/23117775 <Internet> http://jama.jamanetwork.com/article.aspx?articleid=1389615
    Lonn EM Multivitamins in Prevention of Cardiovascular Disease JAMA. 2012;308(17):1802-1803 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/23117781 <Internet> http://jama.jamanetwork.com/article.aspx?articleid=1389595
  7. Madden MM et al Market Analysis of Vitamin Supplementation in Infants and Children. Evidence From the Dietary Supplement Label Database. JAMA Pediatr. Published online January 27, 2014. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/24473529 <Internet> http://archpedi.jamanetwork.com/article.aspx?articleid=1815477
  8. Prescriber's Letter 21(5): 2014 CHART: Multivitamins: Who Needs Them? PDF: Clinically Significant Drug-Induced Nutrient Depletion Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=300511&pb=PRL (subscription needed) http://www.prescribersletter.com
  9. Geriatric Review Syllabus, 8th edition (GRS8) Durso SC and Sullivan GN (eds) American Geriatrics Society, 2013
  10. Bjelakovic G, Gluud C. Vitamin and mineral supplement use in relation to all-cause mortality in the Iowa Women's Health Study. Arch Intern Med. 2011 Oct 10;171(18):1633-4. PMID: https://www.ncbi.nlm.nih.gov/pubmed/21987193
    Mursu J, Robien K, Harnack LJ, Park K, Jacobs DR Jr. Dietary supplements and mortality rate in older women: the Iowa Women's Health Study. Arch Intern Med. 2011 Oct 10;171(18):1625-33. PMID: https://www.ncbi.nlm.nih.gov/pubmed/21987192
  11. 11.0 11.1 The NNT: Vitamin and Antioxidant Supplements for Primary Prevention of Cardiovascular Disease. http://www.thennt.com/nnt/vitamins-and-antioxidants-for-primary-prevention-of-cardiovascular-disease/
  12. Moyer VA; U.S. Preventive Services Task Force. Vitamin, mineral, and multivitamin supplements for the primary prevention of cardiovascular disease and cancer: U.S. Preventive services Task Force recommendation statement. Ann Intern Med. 2014 Apr 15;160(8):558-64. PMID: https://www.ncbi.nlm.nih.gov/pubmed/24566474
  13. Manson JE, Bassuk SS. Vitamin and Mineral Supplements. What Clinicians Need to Know. JAMA. Published online February 5, 2018. PMID: https://www.ncbi.nlm.nih.gov/pubmed/29404568 https://jamanetwork.com/journals/jama/fullarticle/2672264
  14. 14.0 14.1 Kim J, Choi J, Kwon SY et al Association of Multivitamin and Mineral Supplementation and Risk of Cardiovascular Disease. A Systematic Review and Meta-Analysis Circulation: Cardiovascular Quality & Outcomes. 2018;11:e004224. July 10, 2018 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/29991644 <Internet> http://circoutcomes.ahajournals.org/content/11/7/e004224
    Haslam A, Prasad V. Multivitamins Do Not Reduce Cardiovascular Disease and Mortality and Should Not Be Taken for This Purpose. How Do We Know That? <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/29991647 <Internet> http://circoutcomes.ahajournals.org/content/11/7/e004886
  15. 15.0 15.1 Medical Knowledge Self Assessment Program (MKSAP) 18, American College of Physicians, Philadelphia 2018
  16. Khan SU, Khan MU, Riaz H et al Effects of Nutritional Supplements and Dietary Interventions on Cardiovascular Outcomes: An Umbrella Review and Evidence Map. Ann Intern Med. 2019. July 9. PMID: https://www.ncbi.nlm.nih.gov/pubmed/31284304 https://annals.org/aim/article-abstract/2737825/effects-nutritional-supplements-dietary-interventions-cardiovascular-outcomes-umbrella-review-evidence
    Pandey AC, Topol EJ Dispense With Supplements for Improving Heart Outcomes. Ann Intern Med. 2019. July 9. PMID: https://www.ncbi.nlm.nih.gov/pubmed/31284306 https://annals.org/aim/article-abstract/2737826/dispense-supplements-improving-heart-outcomes
  17. 17.0 17.1 17.2 Lou N USPSTF Still Not Swayed on Vitamins to Prevent Heart Disease, Cancer
    Vitamin E, beta-carotene singled out as supplements to be avoided. MedPage Today May 4, 2021 https://www.medpagetoday.com/primarycare/preventivecare/92402
  18. 18.0 18.1 Manson JE Multivitamins Slow Cognitive Aging in Older Adults. Medscape. December 10, 2021 https://www.medscape.com/viewarticle/963748
    Anderson P Multivitamins, but Not Cocoa, Tied to Slowed Brain Aging. Medscape. November 11, 2021. https://www.medscape.com/viewarticle/962772
    ClinicalTrials.gov COcoa Supplement and Multivitamin Outcomes Study for the Mind (COSMOS-Mind). https://clinicaltrials.gov/ct2/show/NCT03035201
  19. 19.0 19.1 US Preventive Services Task Force Vitamin, Mineral, and Multivitamin Supplementation to Prevent Cardiovascular Disease and Cancer. US Preventive Services Task Force Recommendation Statement. JAMA. 2022;327(23):2326-2333. June 21 PMID: https://www.ncbi.nlm.nih.gov/pubmed/35727271 https://jamanetwork.com/journals/jama/fullarticle/2793446
    O'Connor EA, Evans CV, Ivlev I et al Vitamin and Mineral Supplements for the Primary Prevention of Cardiovascular Disease and Cancer. Updated Evidence Report and Systematic Review for the US Preventive Services Task Force. JAMA. 2022;327(23):2334-2347 PMID: https://www.ncbi.nlm.nih.gov/pubmed/35727272 https://jamanetwork.com/journals/jama/fullarticle/2793447
    Jia J, Cameron NS, Linder JA. Multivitamins and Supplements - Benign Prevention or Potentially Harmful Distraction? JAMA. 2022;327(23):2294-2295 PMID: https://www.ncbi.nlm.nih.gov/pubmed/35727292 https://jamanetwork.com/journals/jama/fullarticle/2793472
  20. 20.0 20.1 20.2 Yeung LK et al Multivitamin supplementation improves memory in older adults: A randomized clinical trial. May 24 PMID: https://www.ncbi.nlm.nih.gov/pubmed/37244291 https://ajcn.nutrition.org/article/S0002-9165(23)48904-6/fulltext
  21. 21.0 21.1 21.2 Baker LD et al. Effects of cocoa extract and a multivitamin on cognitive function: A randomized clinical trial. Alzheimers Dement 2023 Apr; 19:1308. PMID: https://www.ncbi.nlm.nih.gov/pubmed/36102337 PMCID: PMC10011015 (available on 2024-04-01)
  22. 22.0 22.1 22.2 Vyas CM et al Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial and meta-analysis of 3 cognitive studies within COSMOS Am J Clin Nutr. 2024. Jan 18:S0002-9165(23)66342-7 PMID: https://www.ncbi.nlm.nih.gov/pubmed/38244989 https://ajcn.nutrition.org/article/S0002-9165(23)66342-7/fulltext
  23. 23.0 23.1 Loftfield E, O'Connell CP, Abnet CC et al Multivitamin Use and Mortality Risk in 3 Prospective US Cohorts JAMA Netw Open. 2024 Jun 3;7(6):e2418729. PMID: https://www.ncbi.nlm.nih.gov/pubmed/38922615 Free article. https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2820369
    Barnard ND et al. The limited value of multivitamin supplements. JAMA Netw Open 2024 Jun; 7:e2418965. PMID: https://www.ncbi.nlm.nih.gov/pubmed/38922621 Free article https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2820375

Patient information

multivitamin/mineral patient information