prescription

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Introduction

A formula (generally written) for the preparation & administration of any therapy or pharmaceutical agent.

* for hand written prescriptions given to patient, write out full name of medication and full description of method of administration i.e. nitroglycerin 0.4 mg sublingual as needed

Management

  • prior to prescribing medication, ask
    • is the medication really necessary?
      • are there alternative nonpharmacologic treatments?
    • what are the therapeutic endpoints?
      • how will they be assessed?
    • do the benefits outweigh the risks?
    • is one medication being used to treat adverse effects of another?
    • is there 1 medication that can be used to treat 2 conditions?
    • are there potential drug-drug interactions or drug-disease interactions?
    • will the administration times coincide with those of current medications?
    • do the patient & caregiver understand
      • what the medication is for?
      • how to take the medication?
      • how long to take the medication?
      • when the medication should start to work?
      • possible adverse effects?
        • what to do in case of adverse effects?
  • general principles
    • start with a low dose (if possible)
    • try not to start 2 medications at once
    • include the indication(s) for the prescription[5][6]
    • use decision support to promote optimum selection of medication[6]
  • followup

Notes

More general terms

More specific terms

Additional terms

References

  1. Stedman's Medical Dictionary 27th ed, Williams & Wilkins, Baltimore, 1999
  2. Morgan SG, Bassett KL, Wright JM, Evans RG, Barer ML, Caetano PA, Black CD. 'Breakthrough' drugs and growth in expenditure on prescription drugs in Canada. BMJ. 2005 Oct 8;331(7520):815-6. Epub 2005 Sep 2. No abstract available. PMID: https://www.ncbi.nlm.nih.gov/pubmed/16141448
  3. Geriatric Review Syllabus, 8th edition (GRS8) Durso SC and Sullivan GN (eds) American Geriatrics Society, 2013
  4. 4.0 4.1 Dreischulte T et al Safer Prescribing - A Trial of Education, Informatics, and Financial Incentives. N Engl J Med 2016; 374:1053-1064. March 17, 2016 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/26981935 <Internet> http://www.nejm.org/doi/full/10.1056/NEJMsa1508955
  5. 5.0 5.1 Schiff GD, Seoane-Vazquez E, Wright A Incorporating Indications into Medication Ordering - Time to Enter the Age of Reason. N Engl J Med 2016; 375:306-309. July 28, 2016 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/27464201 <Internet> http://www.nejm.org/doi/full/10.1056/NEJMp1603964
  6. 6.0 6.1 6.2 Kron K, Myers S, Volk L, et al. Incorporating medication indications into the prescribing process. Am J Health Syst Pharm. 2018 Apr 19; PMID: https://www.ncbi.nlm.nih.gov/pubmed/29674327 https://psnet.ahrq.gov/resources/resource/32145