oxysterol; hydroxysterol

Function

• endogenous ligands of LXR-alpha & LXR-beta
• modulators of cholesterol biosynthesis & other processes
• inhibition HMG CoA reductase (highly purified cholesterol does not)
• induction of apoptosis
• calcification of vascular cells

* All oxysterols may not have all functions*

More general terms

• sterol

More specific terms

• 22-OH-cholesterol
• 24,25-cholesterol epoxide
• 24-OH-cholesterol
• 25-OH-cholesterol
• 27-OH-cholesterol
• 7-ketocholesterol; 7-oxocholesterol
• 7-OH-cholesterol
• cholesterol ozonolysis metabolite 1
• cholesterol ozonolysis metabolite 2
• salinomycin; salinomycinum (Coxistac)

Additional terms

• hydroxymethylglutaryl [HMG] CoA reductase (HMGCR)
• LX nuclear receptor (LXR, oxysterol receptor)
• oxidized low density lipoprotein (oxidized LDL, oxLDL)
• oxysterol-binding protein (OSBP)