cholesterol ozonolysis metabolite 1
Jump to navigation
Jump to search
Introduction
Ozonolysis product of cholesterol. Occurs in human brain during inflammation. The aldehyde moiety covalently binds A-beta accelerating amyloidogenesis.
More general terms
References
- ↑ Zhang, Q et al, Metabolite-initiated protein misfolding may trigger Alzheimer's disease, Proc. Natl. Acad. Sci. USA, 10.1073/pnas.0400924101 http://www.pnas.org/cgi/content/abstract/0400924101