LX nuclear receptor (LXR, oxysterol receptor)
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Introduction
alpha & beta forms. Ligands are oxysterols. LXR binds to RXR to form heterodimers which bind to & activates LXRE enhancer elements.
More general terms
More specific terms
- Oxysterols receptor LXR-alpha; liver X receptor alpha; nuclear orphan receptor LXR-alpha; nuclear receptor subfamily 1 group H member 3 (NR1H3, LXRA)
- oxysterols receptor LXR-beta; liver X receptor beta; nuclear orphan receptor LXR-beta; nuclear receptor subfamily 1 group H member 2; ubiquitously-expressed nuclear receptor; nuclear receptor NER (NR1H2, LXRB, NER, UNR)
Additional terms
References
- ↑ Laffitte BA et al LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes, Proc Natl Acad Sci USA 2001, 98:507 PMID: https://www.ncbi.nlm.nih.gov/pubmed/11149950