25-OH-cholesterol

Function

• endogenous ligand of LXR-alpha & LXR-beta.
• blocks sterol regulatory element binding protein (SREBP) processing
• inhibits cholesterol biosynthesis

More general terms

• oxysterol; hydroxysterol

Additional terms

• cholesterol 25-hydroxylase; cholesterol 25-monooxygenase; h25OH (CH25H)
• LX nuclear receptor (LXR, oxysterol receptor)

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=65094
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=521636