packed red blood cells (RBCs)

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Introduction

A unit of packed RBCs is obtained from centrifugation of 500 mLof whole blood.

200 mL of plasma is separated leaving a volume of 300 mL & a hematocrit of 70-80% in a unit of packed of red blood cells.

Constituents

Indications

Perioperative guidelines:

In hospital guidelines:

Storage

at 6 degrees centigrade

Procedure

Notes

Special preparations

Prevention of RBC transfusions

  • small-volume blood collection tubes
    • 10 fewer units/100 patients per ICU stay
    • small-volume tubes almost always provide sufficient blood for analysis[15]

More general terms

Additional terms

References

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    Medical Knowledge Self Assessment Program (MKSAP) 19 Board Basics. An Enhancement to MKSAP19. American College of Physicians, Philadelphia 2022
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    Carson JL Blood Transfusion and Risk of InfectionNew Convincing Evidence. JAMA. 2014;311(13):1293-1294. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/24691604 <Internet> http://jama.jamanetwork.com/article.aspx?articleid=1853139
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    Tobian AA, Ness PM Red Cells - Aging Gracefully in the Blood Bank. N Engl J Med. October 24, 2016 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/27775504 <Internet> http://www.nejm.org/doi/full/10.1056/NEJMe1612444
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  16. Perioperative Red Cell Transfusion: NIH Consensus Statement http://consensus.nih.gov/cons/070/070_intro.htm