ABO blood group locus
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Structure
- blood group ABO involves three carbohydrate antigens: A,B, & H
- A, B, & AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-galNAc) or to the B antigen (by addition of UDP-gal), whereas O individuals lack such activity
Pathology
- ABO blood type: AB (1.23), B (1.15), & A (1.08), (risk relative to those with type O blood)[2]
More general terms
References
- ↑ OMIM https://mirror.omim.org/entry/110300
- ↑ 2.0 2.1 He M, Wolpin B, Rexrode K et al ABO Blood Group and Risk of Coronary Heart Disease in Two Prospective Cohort Studies ATVBAHA.112.248757, August 14, 2012 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/22895671 <Internet> http://atvb.ahajournals.org/content/early/2012/08/14/ATVBAHA.112.248757.abstract