blood group Rh(D) polypeptide; rhesus D antigen; RHXIII; Rh polypeptide 2; RhPII; CD240D (RHD)

Function

• may be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane

Structure

• belongs to the ammonium transporter (TC 2.A.49) family, Rh subfamily

Compartment

membrane

Alternative splicing

named isoforms=3

Expression

• restricted to tissues or cell lines expressing erythroid characteristics

Polymorphism

• RHD & RHCE are responsible for the Rh blood group system
• the molecular basis of the tar=Rh40 blood group antigen is a polymorphism in position 110

More general terms

• transmembrane 11 protein
• blood group antigen
• CD antigen

Additional terms

• Rh isoimmunization (Rh disease)
• Rhesus blood group cluster

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6007
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6007
• OMIM: https://mirror.omim.org/entry/111680
• UniProt: http://www.uniprot.org/uniprot/Q02161.html