para-aminosalicylate; PAS; 4-aminosalicylate (Pamisyl, Paser)

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Indications

Contraindications

Warnings:

Dosage

  • adults: 12-15 g/day divided TID-QID
  • children: 240-360 mg/kg/day divdided TID-QID
  • take with food
  • avoid exposing drug to moisture, extreme heat or direct sunlight

Tabs: 500 mg, Granules

Pharmacokinetics

elimination via intestine

elimination via liver

elimination via kidney

1/2life = 1 hour

protein binding = 50-70 %

Adverse effects

Drug interactions

Test interactions

More general terms

References

  1. Kaiser Permanente Northern California Regional Drug Formulary, 1998
  2. RxList http://www.rxlist.com/paser-drug.htm
  3. 3.0 3.1 Deprecated Reference
  4. 4.0 4.1 4.2 Medical Knowledge Self Assessment Program (MKSAP) 17, 18. American College of Physicians, Philadelphia 2015, 2018

Database