cerebrospinal fluid

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  • pulsatility of the small penetrating arteries in the brain declines with age[5]
  • reduction of CSF influx into brain parenchyma with age


CSF protein electrophoresis (after concentration)

Total volume (adult): 150 mL (100-160 mL[3])

CSF: production: 0.35 mL/min, 500 mL/day ,

Also see CSF analysis

Comparative biology

More general terms

Additional terms


  1. Fundamentals of Clinical Chemistry 3rd ed., N.W. Teitz ed., W.B. Saunders, 1988, pg 339
  2. Saunders Manual of Medical Practice, Rakel (ed), WB Saunders, Philadelphia, 1996, pg 1065-67
  3. 3.0 3.1 Tietz Textbook of Clinical Chemistry, 2nd ed. Burtis CA & Ashwood ER (eds), WB Saunders Co, Philadelphia PA, 1993
  4. 4.0 4.1 4.2 Clinical Diagnosis & Management by Laboratory Methods, 19th edition, J.B. Henry (ed), W.B. Saunders Co., Philadelphia, PA. 1996
  5. 5.0 5.1 5.2 5.3 5.4 Glymphatic Flow, Sleep, microRNA Are Frontiers in Alzheimer's Research. Zilkha Symposium on Alzheimer's Disease and Related Disorders May 6, 2014 http://www.alzforum.org/news/conference-coverage/glymphatic-flow-sleep-microrna-are-frontiers-alzheimers-research
  6. Spector R, Robert Snodgrass S, Johanson CE. A balanced view of the cerebrospinal fluid composition and functions: Focus on adult humans. Exp Neurol. 2015 Nov;273:57-68. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/26247808 Free Article
  7. lumen Anatomy & Physiology. Module 12. The Nervous System Circulation and Protection of the CNS The Ventricular System Dural Sinuses and Veins https://courses.lumenlearning.com/austincc-ap1/chapter/circulation-and-the-central-nervous-system/#m46719-fig-ch13_03_04