Bcl-2 homologous antagonist/killer; apoptosis regulator BAK; Bcl-2-like protein 7; Bcl2-L-7 (BAK1, BAK, BCL2L7, CDN1)

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Function

Structure

Compartment

mitochondrial outer membrane

Expression

  • expressed in wide variety of cell types
  • highest levels in the heart & skeletal muscle

More general terms

Additional terms

References

  1. Farrow SN, White JH, Martinou I, Raven T, Pun KT, Grinham CJ, Martinou JC, Brown R. Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K. Nature. 1995 Apr 20;374(6524):731-3. Erratum in: Nature 1995 Jun 1;375(6530):431. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7715729
  2. Chittenden T, Harrington EA, O'Connor R, Flemington C, Lutz RJ, Evan GI, Guild BC. Induction of apoptosis by the Bcl-2 homologue Bak. Nature. 1995 Apr 20;374(6524):733-6. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7715730
  3. Kiefer MC, Brauer MJ, Powers VC, Wu JJ, Umansky SR, Tomei LD, Barr PJ. Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak. Nature. 1995 Apr 20;374(6524):736-9. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7715731
  4. Adams JM, Cory S. Life-or-death decisions by the Bcl-2 protein family. Trends Biochem Sci. 2001 Jan;26(1):61-6. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/11165519
  5. Entrez Gene http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=578
  6. UniProt http://www.uniprot.org/uniprot/Q16611.html
  7. NIEHS-SNPs http://egp.gs.washington.edu/data/bak1/

Database