bcl-2 homology 3 (BH3) domain

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[1]

Introduction

A death domain characteristic of pro-apoptotic bcl-2 family members. It is an amphipathic alpha helical sequence & a binding site for ligand interactions.

More general terms

References

  1. ↑ Adams JM, Cory S. Life-or-death decisions by the Bcl-2 protein family. Trends Biochem Sci. 2001 Jan;26(1):61-6. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/11165519
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