unfolded protein response; misfolded protein response; proteostasis; endoplasmic reticulum associated protein degradation (UPR, ERAD)

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Pathology

Physiology

More general terms

References

  1. Larner SF, Hayes RL, Wang KK. Unfolded protein response after neurotrauma. J Neurotrauma. 2006 Jun;23(6):807-29. PMID: https://www.ncbi.nlm.nih.gov/pubmed/16774469
  2. 2.0 2.1 Doody GM, Stephenson S, Tooze RM. BLIMP-1 is a target of cellular stress and downstream of the unfolded protein response. Eur J Immunol. 2006 Jun;36(6):1572-82. PMID: https://www.ncbi.nlm.nih.gov/pubmed/16708403
  3. UniProt http://www.uniprot.org/uniprot/P55072.html
  4. 4.0 4.1 Kaufman R, University of Michigan Proceedings of the 38th Annual Meeting of the American Aging Association: Integrative Biology: Hormones, Signaling, and Aging. May 29-June 1, 2009, Scottsdale, AZ
  5. Wikipedia: Endoplasmic Reticulum Associated Protein Degradation http://en.wikipedia.org/wiki/Endoplasmic_Reticulum_Associated_Protein_Degradation
  6. 6.0 6.1 6.2 Tsaytler P et al. Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis. Science 2011 Apr 1; 332:91. PMID: https://www.ncbi.nlm.nih.gov/pubmed/21385720
  7. Alavez S et al. Amyloid-binding compounds maintain protein homeostasis during ageing and extend lifespan. Nature 2011 Apr 14; 472:226 PMID: https://www.ncbi.nlm.nih.gov/pubmed/21451522
  8. 8.0 8.1 8.2 Geriatric Review Syllabus, 11th edition (GRS11) Harper GM, Lyons WL, Potter JF (eds) American Geriatrics Society, 2022
  9. 9.0 9.1 Wajngarten M Is There Hope in the Fight Against Aging? Medscape. December 19, 2022 https://www.medscape.com/viewarticle/985809