Blimp-1 protein; B lymphocyte-induced maturation protein; PR-domain zinc finger protein 1; beta-interferon gene positive-regulatory domain I binding factor; positive regulatory domain I-binding factor 1; PRDI-binding factor-1 (BLIMP1, PRDM1, PRD1-BF)
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Function
- elevated expression of blimp-1 protein in mature B cells results in J chain transcription, expression of syndecan-1 & onset of IgM secretion
Expression
- expressed in activated B cells & plasma cells
More general terms
References
- ↑ Huang S. Blimp-1 is the murine homolog of the human transcriptional repressor PRDI-BF1. Cell. 1994 Jul 15;78(1):9. No abstract available. PMID: https://www.ncbi.nlm.nih.gov/pubmed/8033216
- ↑ UniProt http://www.uniprot.org/uniprot/O75626.html