NGLY1-SAKS1-AMFR-VCP-RAD23B complex

Function

• complex required to couple retrotransloaction, ubiquitination, deglycosylation & proteasome-mediated degradation of misfolded proteins

Structure

• consists of: NGLY1, SAKS1, AMFR, VCP & RAD23B

Compartment

endoplasmic reticulum

More general terms

• molecular complex