ubiquitin-conjugating enzyme E2 L3; L-UBC; UbcH7; ubiquitin carrier protein L3; ubiquitin-conjugating enzyme E2-F1; ubiquitin-protein ligase L3 (UBE2L3, UBE2L1, UBCE7, UBCH7)

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Function

Structure

Compartment

Expression

Pathology

Notes

  • 2 genes for ubiquitin-conjugating proteins UBE2L1/UBE2L3 are identical except that the E2L1 gene is intronless, while the E2L3 coding sequence is interrupted by 3 introns[1]
  • UBE2L1, UBE2L2 & UBE2L4 are most likely pseudogenes & the only expressed member of this subfamily seems to be UBE2L3[3]

More general terms

References

  1. 1.0 1.1 UniProt http://www.uniprot.org/uniprot/P68036.html
  2. OMIM https://mirror.omim.org/entry/600012
  3. 3.0 3.1 Ardley HC et al Promoter analysis of the human ubiquitin-conjugating enzyme gene family UBE2L1-4, including UBE2L3 which encodes UbcH7 Biochim Biophys Acta. 2000 Apr 25;1491(1-3):57-64. PMID: https://www.ncbi.nlm.nih.gov/pubmed/10760570

Database