matrix metalloproteinase-2 (matrixin-2, TBE-1, 72 kD gelatinase, gelatinase A, MMP2, CLG4A)

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Function

Cofactor:

  • binds 4 Ca+2 per subunit
  • binds 2 Zn+2 per subunit

Structure

Expression

produced by normal skin fibroblasts

Pathology

Laboratory

More general terms

References

  1. UniProt http://www.uniprot.org/uniprot/P08253.html
  2. Chang C, Werb Z. The many faces of metalloproteases: cell growth, invasion, angiogenesis and metastasis. Trends Cell Biol. 2001 Nov;11(11):S37-43. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/11684441
  3. Atlas of Genetics & Cytogenetics in Oncology & Haematology http://atlasgeneticsoncology.org/genes/MMP2ID41396ch16q13.html

Database