collagenase-4 or gelatinase

Introduction

At least 2 forms

Function

• specifically cleaves type IV collagen (basement membrane)
• metastatic potential of transformed cells correlates with collagenase-4 activity

More general terms

• collagenase
• metalloprotein

More specific terms

• matrix metalloproteinase-2 (matrixin-2, TBE-1, 72 kD gelatinase, gelatinase A, MMP2, CLG4A)
• matrix metalloproteinase-9 (matrixin-9, 92 kD gelatinase, gelatinase-B, MMP9, CLG4B)

Database

• OMIM: https://mirror.omim.org/entry/120360