centaurin-beta-1; Arf-GAP with coiled-coil, ANK repeat & PH domain-containing protein 1; Cnt-b1 (ACAP1, CENTB1, KIAA0050)

From Aaushi
Jump to navigation Jump to search

Function

Structure

Expression

  • highest level in lung & spleen
  • low level in heart, kidney, liver & pancreas

Notes

  • cells overexpressing ACAP1 show an accumulation of ITGB1 in recycling endosomes & inhibition of stimulation- dependent cell migration
  • cells with reduced levels of ACAP1 or AKT1 & AKT2 show inhibition of stimulation-dependent cell migration
  • cells overexpressing ACAP1 & PIP5K1C show formation of tubular structures derived from endosomal membranes

More general terms

Additional terms

References

Database