myosin-6; unconventional myosin-6 (MYO6, KIAA0389)

From Aaushi
Jump to navigation Jump to search

Function

Structure

  • homodimer
  • divided into three regions:
    • N-terminal motor (head) domain
    • neck domain consisting of a calmodulin-binding linker domain & a single IQ motif
    • C-terminal tail region with a coiled-coil & a unique globular domain required for interaction with other proteins
  • contains 1 IQ domain
  • contains 1 myosin head-like domain

Compartment

Alternative splicing

named isoforms=5

Expression

Pathology

More general terms

Additional terms

References

Database