golgi
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Introduction
A stacked array of membranous cisternae & connecting tubules or vesicles between the nucleus & the secretory pole of a cell. It is receives nascent polypeptides from the endoplasmic reticulum, destined for the secretory pathway.
Classification
- cis, trans & intermediate GOLGI compartments have been described
Function
3 major functions:[2]
- carbohydrate processing & modification of proteins & lipids moving through the secretory pathway
- protein sorting & transport, receiving membrane from the ER & delivering it to the plasma membrane or other intracellular sites
- membrane scaffold onto which diverse signaling, sorting & cytoskeleton proteins adhere
More general terms
More specific terms
Additional terms
References
- ↑ Stedman's Medical Dictionary 27th ed, Williams & Wilkins, Baltimore, 1999.
- ↑ 2.0 2.1 Altan-Bonnet N, Sougrat R, Lippincott-Schwartz J. Molecular basis for Golgi maintenance and biogenesis. Curr Opin Cell Biol. 2004 Aug;16(4):364-72. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/15261668
- ↑ de Graffenried CL, Bertozzi CR. The roles of enzyme localisation and complex formation in glycan assembly within the Golgi apparatus. Curr Opin Cell Biol. 2004 Aug;16(4):356-63. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/15261667
- ↑ Colanzi A, Suetterlin C, Malhotra V. Cell-cycle-specific Golgi fragmentation: how and why? Curr Opin Cell Biol. 2003 Aug;15(4):462-7. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/12892787
- ↑ Barr FA, Short B. Golgins in the structure and dynamics of the Golgi apparatus. Curr Opin Cell Biol. 2003 Aug;15(4):405-13. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/12892780
- ↑ Bankaitis VA, Morris AJ. Lipids and the exocytotic machinery of eukaryotic cells. Curr Opin Cell Biol. 2003 Aug;15(4):389-95. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/12892778
- ↑ Ponnambalam S, Baldwin SA. Constitutive protein secretion from the trans-Golgi network to the plasma membrane. Mol Membr Biol. 2003 Apr-Jun;20(2):129-39. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/12851070
- ↑ Rabouille C, Jokitalo E. Golgi apparatus partitioning during cell division. Mol Membr Biol. 2003 Apr-Jun;20(2):117-27. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/12851069
- ↑ Machamer CE. Golgi disassembly in apoptosis: cause or effect? Trends Cell Biol. 2003 Jun;13(6):279-81. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/12791290