bBAF complex (brain-specific chromatin remodeling complex)

Function

• chromatin remodeling
• role in remodeling mononucleosomes (ATP-dependent)

Structure

• subunits: actin (ACTB), ARID1A/BAF250, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCC2/BAF170, SMARCD2/BAF60B & SMARCE1/BAF57

Notes

• the bBAF complex is polymorphic in regard to the ATPase, SMARCA2 & SMARCA4 occupying mutually exclusive positions
• PBRM1 does not belong to bBAF complex

More general terms

• SWI/SNF-A (BAF) chromatin remodeling complex

Additional terms

• nBAF complex (neuron-specific chromatin remodeling complex)
• npBAF complex (neural progenitors-specific chromatin remodeling complex)