protein polybromo-1; hPB1; polybromo-1D; BRG1-associated factor 180 (PBRM1, BAF180, PB1)

Function

• role in transcriptional activation & repression by chromatin
• component of the SWI/SNF chromatin-remodeling complex

Structure

• contains 2 BAH domains contains 6 bromo domains contains 1 HMG box DNA-binding domain

Compartment

nucleus

Alternative splicing

named isoforms=6

Expression

widely expressed

More general terms

• nuclear protein
• phosphoprotein

Component of

• SWI/SNF-B (PBAF) chromatin remodeling complex

Database

• OMIM: https://mirror.omim.org/entry/606083
• UniProt: http://www.uniprot.org/uniprot/Q86U86.html