critical disease; critical illness; critically ill patient; critical condition

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Introduction

Also see critical illness syndrome, critical care medicine & intensive care unit

Etiology

Pathology

Clinical manifestations

Laboratory

Diagnostic procedures

Complications

Management

More general terms

More specific terms

Additional terms

References

  1. Jump up to: 1.0 1.1 The National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network. Initial trophic vs full enteral feeding in patients with acute lung injury: The EDEN randomized trial. JAMA 2012 Feb 22/29; 307:795 PMID: https://www.ncbi.nlm.nih.gov/pubmed/22307571
    Griffiths RD. Nutrition for critically ill patients: How much is enough? JAMA 2012 Feb 22/29; 307:845 PMID: https://www.ncbi.nlm.nih.gov/pubmed/22307570
  2. Jump up to: 2.0 2.1 2.2 2.3 Boonen E et al. Reduced cortisol metabolism during critical illness. N Engl J Med 2013 Mar 19 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/23506003 <Internet> http://www.nejm.org/doi/full/10.1056/NEJMoa1214969
  3. Jump up to: 3.0 3.1 3.2 3.3 3.4 Medical Knowledge Self Assessment Program (MKSAP) 16, 17, 19. American College of Physicians, Philadelphia 2012, 2015, 2022.
  4. Jump up to: 4.0 4.1 Pandharipande PP et al. Long-term cognitive impairment after critical illness. N Engl J Med 2013 Oct 3; 369:1306 PMID: https://www.ncbi.nlm.nih.gov/pubmed/24088092
  5. Adler SM1, Verbalis JG. Disorders of body water homeostasis in critical illness. Endocrinol Metab Clin North Am. 2006 Dec;35(4):873-94 PMID: https://www.ncbi.nlm.nih.gov/pubmed/17127152
  6. Jump up to: 6.0 6.1 Harvey SE et al. Trial of the route of early nutritional support in critically ill adults. N Engl J Med 2014 Oct 1 PMID: https://www.ncbi.nlm.nih.gov/pubmed/25271389
  7. Jump up to: 7.0 7.1 7.2 Arabi YM et al. Permissive underfeeding or standard enteral feeding in critically ill adults. N Engl J Med 2015 Jun 18; 372:2398 PMID: https://www.ncbi.nlm.nih.gov/pubmed/25992505
  8. Ferrante LE, Pisani MA, Murphy TE, et al. Functional trajectories among older persons before and after critical illness. JAMA Intern Med. 2015;175(4):523-529. PMID: https://www.ncbi.nlm.nih.gov/pubmed/25665067
    Covinsky KE. The critical importance of functional status in critical illness. JAMA Intern Med. 2015;175(4):530. PMID: https://www.ncbi.nlm.nih.gov/pubmed/25665038
  9. Jump up to: 9.0 9.1 9.2 9.3 9.4 9.5 Taylor BE, McClave SA, Martindale RG et al Guidelines for the Provision and Assessment of Nutrition Support Therapy in the Adult Critically Ill Patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.). Crit Care Med. 2016 Feb;44(2):390-438. PMID: https://www.ncbi.nlm.nih.gov/pubmed/2677178
  10. Jump up to: 10.0 10.1 Carson SS, Cox CE, Wallenstein S et al Effect of Palliative Care-Led Meetings for Families of Patients With Chronic Critical Illness: A Randomized Clinical Trial. JAMA. 2016 Jul 5;316(1):51-62. PMID: https://www.ncbi.nlm.nih.gov/pubmed/27380343
    White DB. Strategies to Support Surrogate Decision Makers of Patients With Chronic Critical Illness: The Search Continues. JAMA. 2016 Jul 5;316(1):35-7. PMID: https://www.ncbi.nlm.nih.gov/pubmed/27380340
  11. Jump up to: 11.0 11.1 11.2 Reignier J, Boisrame-Helms J, Brisard L et al. Enteral versus parenteral early nutrition in ventilated adults with shock: A randomised, controlled, multicentre, open-label, parallel-group study (NUTRIREA-2). Lancet 2017 Nov 8; [e-pub]. PMID: https://www.ncbi.nlm.nih.gov/pubmed/29128300
    Van Dyck L, Casaer MP. Nutrition in the ICU: Sometimes route does matter. Lancet 2017 Nov 8 PMID: https://www.ncbi.nlm.nih.gov/pubmed/29128299
  12. Jump up to: 12.0 12.1 Mathews KS, Durst, MS. Vargas-Torres C et al. Effect of emergency department and ICU occupancy on admission decisions and outcomes for critically ill patients. Crit Care Med 2018 Jan 30; PMID: https://www.ncbi.nlm.nih.gov/pubmed/29384780 https://journals.lww.com/ccmjournal/Abstract/publishahead/Effect_of_Emergency_Department_and_ICU_Occupancy.96357.aspx
  13. Higgs A, McGrath BA, Goddard C, et al. Guidelines for the management of tracheal intubation in critically ill adults. Br J Anaesth. 2018 Feb;120(2):323-352. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/29406182 <Internet> http://bjanaesthesia.org/article/S0007-0912(17)54060-X/fulltext
  14. Jump up to: 14.0 14.1 14.2 Hill CE, Blank LJ, Thibault D et al. Continuous EEG is associated with favorable hospitalization outcomes for critically ill patients. Neurology 2019 Jan 1; 92:e9. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/30504428 <Internet> http://n.neurology.org/content/92/1/e9
  15. Jump up to: 15.0 15.1 The National Heart, Lung, and Blood Institute PETAL Clinical Trials Network. Early high-dose vitamin D3 for critically ill, vitamin D-deficient patients. N Engl J Med 2019 Dec 26; 381:2529 PMID: https://www.ncbi.nlm.nih.gov/pubmed/31826336 https://www.nejm.org/doi/10.1056/NEJMoa1911124
  16. Jump up to: 16.0 16.1 Deane AM, Little L, Bellomo R et al. Outcomes six months after delivering 100% or 70% of enteral calorie requirements during critical illness (TARGET): A randomized controlled trial. Am J Respir Crit Care Med 2020 Apr 1; 201:814. PMID: https://www.ncbi.nlm.nih.gov/pubmed/31904995 https://www.atsjournals.org/doi/10.1164/rccm.201909-1810OC
  17. Jump up to: 17.0 17.1 Rubin EB, Buehler A, Halpern SD. Seriously ill patients' willingness to trade survival time to avoid high treatment intensity at the end of life. JAMA Intern Med 2020 Apr 6; PMID: https://www.ncbi.nlm.nih.gov/pubmed/32250436 https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2763718
  18. Jump up to: 18.0 18.1 Gelissen H, de Grooth HJ, Smulders Y et al. Effect of low-normal vs high-normal oxygenation targets on organ dysfunction in critically ill patients: A randomized clinical trial. JAMA 2021 Aug 31; [e-pub] PMID: https://www.ncbi.nlm.nih.gov/pubmed/34463696 https://jamanetwork.com/journals/jama/article-abstract/2783810
  19. Jump up to: 19.0 19.1 Finfer S, Micallef S, Hammond N et al Balanced multielectrolyte solution versus saline in critically ill adults. N Engl J Med 2022 Jan 18; [e-pub] PMID: https://www.ncbi.nlm.nih.gov/pubmed/35041780 https://www.nejm.org/doi/10.1056/NEJMoa2114464
  20. Jump up to: 20.0 20.1 Paton M et al. The effect of mobilization at 6 months after critical illness - Meta-analysis. NEJM Evid 2023 Feb; 2:EVIDoa2200234. PMID: https://www.ncbi.nlm.nih.gov/pubmed/38320036 https://evidence.nejm.org/doi/10.1056/EVIDoa2200234
    The TEAM Study Investigators and the ANZICS Clinical Trials Group. Early active mobilization during mechanical ventilation in the ICU. N Engl J Med 2022 Nov 10; 387:1747. PMID: https://www.ncbi.nlm.nih.gov/pubmed/36286256 https://www.nejm.org/doi/10.1056/NEJMoa2209083
  21. Jump up to: 21.00 21.01 21.02 21.03 21.04 21.05 21.06 21.07 21.08 21.09 21.10 Herridge MS, Azoulay E. Outcomes after Critical Illness. N Engl J Med 2023; 388:913-924 PMID: https://www.ncbi.nlm.nih.gov/pubmed/36884324 https://www.nejm.org/doi/full/10.1056/NEJMra2104669