small G protein signaling modulator 1; RUN & TBC1 domain-containing protein 2 (SGSM1, RUTBC2, KIAA1941)

Function

• rab GTPase-activating protein (putative)
• interacts with RAB3A, RAB4A, RAB5A, RAB8A, RAB11A, RAP1A, RAP1B, RAP2A and RAP2B
• no interaction with RAB27A Strucure:
• belongs to the RUTBC family
• contains 1 Rab-GAP TBC domain
• contains 1 RUN domain

Compartment

Golgi, trans-Golgi network

Alternative splicing

named isoforms=3

Expression

mainly expressed in brain, heart & testis

More general terms

• rab GTPase-activating protein (rab-GAP)

Database

• UniProt: http://www.uniprot.org/uniprot/Q2NKQ1.html