rab11a proto-oncogene protein; Ras-related protein Rab-11A; Rab-11; 24KG; YL8 (RAB11A. RAB11)

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Function

endocytic recycling via endosomes & trans GOLGI network; modulates endosomal trafficking (putative)
interacts with RAB11FIP1, RAB11FIP2, RAB11FIP3 & RAB11FIP4
binds RIP11 & STXBP6.
interacts with SGSM1, SGSM2 & SGSM3 (putative)

Structure

belongs to the small GTPase superfamily, Rab family

Compartment

cell membrane; peripheral membrane protein
recycling endosome membrane
translocates with RAB11FIP2 from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane

More general terms

rab subfamily protein

References

↑ Seabra MC et al Rab GTPases, intracellular traffic and disease Trends in Molecular Medicine 8:23, 2002 PMID: https://www.ncbi.nlm.nih.gov/pubmed/11796263
↑ Entrez Gene http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=8766
↑ UniProt http://www.uniprot.org/uniprot/P62491.html

Database

UniProt: http://www.uniprot.org/uniprot/P62491.html
Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=8766
Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8766
OMIM: https://mirror.omim.org/entry/605570

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