small G protein signaling modulator 2; RUN & TBC1 domain-containing protein 1 (SGSM2, RUTBC1, KIAA0397)

Function

• interacts with RAB4A, RAB11A, RAP1A, RAP1B, RAP2A & RAP2B
• no interaction with RAB27A

Structure

• belongs to the RUTBC family
• contains 1 Rab-GAP TBC domain
• contains 1 RUN domain

Alternative splicing

named isoforms=5

Expression

widely expressed

More general terms

• rab GTPase-activating protein (rab-GAP)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9905
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:9905
• OMIM: https://mirror.omim.org/entry/611418
• UniProt: http://www.uniprot.org/uniprot/O43147.html