Rab11 family-interacting protein 1 (Rab11-FIP1, Rab-coupling protein, RAB11FIP1, RCP)

Function

• Rab11 effector protein
• endosomal recycling process
• membrane trafficking along the phagocytic pathway
• phagocytosis
• Isoform 2 interacts with RAB4A, RAB11A, RAB11B & RAB25

Structure

• homooligomer (isoform 2)
• contains 1 C2 domain

Compartment

• recycling endosome, cytoplasmic vesicle, phagosome membrane-bound (isoform 2)
• colocalizes with Rab11A at phagosomes (isoform 2)

Alternative splicing

named isoforms=5

Expression

• isoform 2 is expressed in brain, heart, testis, lung, spleen, ovary, small intestine

More general terms

• phosphoprotein

Database

• OMIM: https://mirror.omim.org/entry/608737
• UniProt: http://www.uniprot.org/uniprot/Q6WKZ4.html