rab8a proto-oncogene protein; Ras-related protein Rab-8A; mel proto-oncogene protein (RAB8A, MEL, RAB8)
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Function
- polarized secretion
- trans-GOLGI network-basolateral plasma membrane transport
- role in vesicular trafficking & neurotransmitter release
- interacts with MAP4K2 & SYTL4. interacts with SGSM1 & SGSM3 (putative)
Structure
belongs to the small GTPase superfamily, Rab family
Compartment
- cell membrane; lipid-anchor; cytoplasmic side (putative)
More general terms
References
- ↑ Kahn RA, Der CJ, Bokoch GM. The ras superfamily of GTP-binding proteins: guidelines on nomenclature. FASEB J. 1992 May;6(8):2512-3. PMID: https://www.ncbi.nlm.nih.gov/pubmed/1592203
- ↑ Seabra MC et al Rab GTPases, intracellular traffic and disease Trends in Molecular Medicine 8:23, 2002 PMID: https://www.ncbi.nlm.nih.gov/pubmed/11796263
- ↑ Entrez Gene http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=4218
- ↑ UniProt http://www.uniprot.org/uniprot/P61006.html