anti-NMDA receptor encephalitis; NMDAR Ab encephalitis

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Etiology

Epidemiology

  • 80% women
  • most commonly occurs age 2-40 years[4]

Pathology

Clinical manifestations

Laboratory

Diagnostic procedures

Radiology

Differential diagnosis

Management

Prognosis:

More general terms

Additional terms

References

  1. 1.0 1.1 1.2 1.3 Medical Knowledge Self Assessment Program (MKSAP) 16, 17, 18. American College of Physicians, Philadelphia 2012, 2015, 2018.
  2. 2.0 2.1 Dalmau J, Gleichman AJ, Hughes EG et al Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies. Lancet Neurol. 2008 Dec;7(12):1091-8 PMID: https://www.ncbi.nlm.nih.gov/pubmed/18851928
  3. Titulaer MJ, McCracken L, Gabilondo I et al Treatment and prognostic factors for long-term outcome in patients with anti-NMDA receptor encephalitis: an observational cohort study. Lancet Neurol. 2013 Feb;12(2):157-65. PMID: https://www.ncbi.nlm.nih.gov/pubmed/23290630 Free PMC Article
  4. 4.00 4.01 4.02 4.03 4.04 4.05 4.06 4.07 4.08 4.09 4.10 4.11 4.12 4.13 4.14 Mathai SK, Josephson SA, Badlam J et al Scratching Below the Surface. N Engl J Med 2016; 375:2188-2193. December 1, 2016 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/27959764 <Internet> http://www.nejm.org/doi/full/10.1056/NEJMcps1603154
  5. Dalmau J, Graus F. Antibody-Mediated Encephalitis. N Engl J Med. 2018 Mar 1;378(9):840-851. PMID: https://www.ncbi.nlm.nih.gov/pubmed/29490181
  6. ARUP Consult: N-methyl-D-Aspartate (NMDA) type Glutamate Receptor Autoantibody Disorders Anti-NMDA-Receptor Encephalitis The Physician's Guide to Laboratory Test Selection & Interpretation https://www.arupconsult.com/content/n-methyl-d-aspartate-nmda-type-glutamate-receptor-autoantibody-disorders
    Anti-NMDA Receptor (NR1) IgG Antibodies https://arupconsult.com/ati/anti-nmda-receptor-nr1-igg-antibodies

Patient information

anti-NMDA receptor encephalitis patient information