AIDS-defining condition

Introduction

Conditions listed in AIDS surveillance case definition:

• malignancies
  • Kaposi's sarcoma, especially < 60 years of age
  • CNS lymphoma, especially < 60 years of age
  • other non-Hodgkin's lymphoma
  • invasive cervical cancer
• Infection
  • Pneumocystis pneumonia
    • Pneumocystis carinii pneumonia (PCP)
    • Pneumocystis jirovecci pneumonia
  • cytomegalovirus (except liver, spleen, lymph nodes)
    • CMV retinitis (with loss of vision)
  • Mycobacterial infection
    • Mycobacterium avium complex (MAC)
      • disseminated
      • involvement of organ(s) other than
        • lung
        • hilar or cervical lymph nodes
        • skin
    • Mycobacterium kansasii (same as MAC)
    • Mycobacterium tuberculosis (extrapulmonary > pulmonary)
    • other extrapulmonary Mycobacteria
  • candidiasis
    • esophagus
    • bronchi, trachea or lungs
  • coccidioidomycosis, disseminated (extrapulmonary)*
  • cryptococcus (extrapulmonary)
  • cryptosporidiosis, chronic intestinal (> 1 month duration)
  • Herpes simplex
    • chronic ulcers > 1 month's duration
    • bronchitis, pneumonia or esophagitis of any duration
  • histoplasmosis, disseminated (extrapulmonary)*
  • isosporiasis, chronic intestinal (> 1 month duration)
  • progressive multifocal leukoencephalopathy (PML)
  • Salmonella septicemia, recurrent
  • Toxoplasmosis of the brain
  • pneumonia, recurrent
• other (may be infectious)
  • encephalopathy (HIV-related)
  • wasting syndrome

*sites other than cervical or hilar lymph nodes

Other conditions not included above:

• bacillary angiomatosis
• candidiasis
  • oropharyngeal
  • vulvovaginal (perisitent, frequent or poorly responsive to therapy)
• cervical dysplasia -> carcinoma in situ
• constitutional symptoms lasting > 1 month
  • fever > 38.5 degrees C
  • diarrhea
• hairy leukoplakia, oral
• shingles (Herpes zoster) involving 2 distinct episodes or more than 1 dermatome
• idiopathic thrombocytopenic purpura (ITP)
• Listeriosis
• pelvic inflammatory disease, especially complicated by tuboovarian abscess
• peripheral neuropathy

Additional terms

• Acquired Immuno-Deficiency Syndrome (HIV infection stage 3, AIDS)
• HIV1 infection; human immunodeficiency virus-1 infection