S-adenosyl methionine (AdoMet, SAM, ademetionine)

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Function

Pharmacology

  • SAMe

Indications

(uses)

* Preliminary suggest SAM-e may be as beneficial as NSAIDs for treatment of osteoarthritis[3]

Contraindications

Dosage

Adverse effects

Drug interactions

Mechanism of action

More general terms

Additional terms

Component of

References

  1. Stryer Biochemistry WH Freeman & Co, New York, 1988 pg 582
  2. 2.0 2.1 Geriatrics Review Syllabus, American Geriatrics Society, 5th edition, 2002-2004; 7th edition 2010
  3. 3.0 3.1 Prescriber's Letter 10(5):27 2003
  4. 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 4.8 Geriatrics at your Fingertips, 13th edition, 2011 Reuben DB et al (eds) American Geriatric Society
  5. 5.0 5.1 5.2 5.3 5.4 Geriatric Review Syllabus, 8th edition (GRS8) Durso SC and Sullivan GN (eds) American Geriatrics Society, 2013
    Geriatric Review Syllabus, 9th edition (GRS9) Medinal-Walpole A, Pacala JT, Porter JF (eds) American Geriatrics Society, 2016
  6. 6.0 6.1 Alpert JE, Papakostas G, Mischoulon D et al S-adenosyl-L-methionine (SAMe) as an adjunct for resistant major depressive disorder: an open trial following partial or nonresponse to selective serotonin reuptake inhibitors or venlafaxine. J Clin Psychopharmacol. 2004 Dec;24(6):661-4. PMID: https://www.ncbi.nlm.nih.gov/pubmed/15538131

Database