5-methylcytosine

Introduction

Methylated base in DNA. Favors the formation of Z-DNA from B-DNA & reduces transcription of genes than contain methylated cytosine in promoter & enhancer regions of the gene. Methyl group provided by S-adenosylmethionine.

More general terms

• pyrimidone

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=65040