rizatriptan (Maxalt, Maxalt-MLT)

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Introduction

Tradenames: Maxalt, Maxalt-MLT. Rizatriptan benzoate.

Indications

migraine headache

Contraindications

Dosage

  • 5-10 mg PO, may repeat in 2 hours
  • maximum: 30 mg QD

Tabs: 5, 10 mg

Sublingual: Maxalt MLT

Pharmacokinetics

elimination via liver

1/2life = 2-3 hours

protein binding = 14 %

Adverse effects

Drug interactions

  • concurrent use of propranolol may increase levels of rizatriptan: reduce dose of rizatriptan[4]

More general terms

Component of

References

  1. Merck & Company
  2. Kaiser Permanente Northern California Regional Drug Formulary (update 3/2000)
  3. Jump up to: 3.0 3.1 Prescriber's Letter 9(2):8 2002
  4. Jump up to: 4.0 4.1 Prescriber's Letter 10(3):14-15 2003
  5. Medscape: rizatriptan (Rx) https://reference.medscape.com/drug/maxalt-maxalt-mlt-rizatriptan-343033

Database