cerivastatin; rivastatin (Baycol, Lipobay)

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Introduction

Tradename: Baycol. Removed from US market 2001[3] Withdrawn from worldwide market Aug 8, 2001[2].

Indications

Contraindications

pregnancy category = x

safety in lactation = -

Dosage

  • 0.4 mg QD in the evening
  • may be given with or without food

Tabs: 0.2, 0.3, 0.4 mg.

store tabs below 77 degrees F; protect from moisture.

Dosage adjustment in renal failure

Pharmacokinetics

elimination via liver

elimination via kidney

protein binding = >99 &

1/2life = 2-3 hours

Monitor

Adverse effects

Drug interactions

Mechanism of action

More general terms

Additional terms

References

  1. Micromedex
  2. 2.0 2.1 http://www.baycol.com/Dear_HealthCare_Letter_Baycol_pull.jpg http://www.press.bayer.com/News/news.nsf/ID/NT0000E072
  3. 3.0 3.1 3.2 Prescriber's Letter 8(9):50 2001
  4. 4.0 4.1 4.2 Psaty BM, Furberg CD, Ray WA, Weiss NS. Potential for conflict of interest in the evaluation of suspected adverse drug reactions: use of cerivastatin and risk of rhabdomyolysis. JAMA. 2004 Dec 1;292(21):2622-31. Epub 2004 Nov 22. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/15572720

Database