creatine kinase

Function

• serves to create energy stores in the form of phosphocreatine in tissues that consume ATP

ATP + creatine <--> ADP + phosphocreatine

Structure

• dimer of identical or non-identical chains
• MM being the major form in skeletal muscle (98-99%) & myocardium (60%)
• MB exists in myocardium (40%), skeletal muscle (1%)
• BB existing in many tissues, especially brain (90%)
• mitochondrial creatine kinases
  • sarcomeric/mitochondrial creatine kinase
  • ubiquitous/mitochondrial creatine kinase

Compartment

• found associated with myofibrillary structures

More general terms

• kinase or ATP-phosphotransferase
• multisubunit protein

More specific terms

• creatine kinase BB
• creatine kinase MB
• creatine kinase MM
• sarcomeric/mitochondrial creatine kinase (S-mtCK, CKMT2)
• ubiquitous/mitochondrial creatine kinase (U-mtCK, CKMT1, CKMT1A, CKMT, CKMT1B, Mia-CK)

Additional terms

• creatine kinase (CK) in serum