drug interaction(s) of statins with fibrates
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Drug interactions
- clinical benefit of statin-fibrate combinations is unclear
- no evidence of additional cardiovascular risk reduction over statin alone
- risk of rhabdomyolysis or severe myalgia is significantly increased with combination therapy
- risk appears to be dose-dependent
More general terms
References
- ↑ Safety of high-dose statin-fibrate combinations National PBM bulletin Nov 10, 2009 Veterans Administration