dematin; dematin actin-binding protein; erythrocyte membrane protein band 4.9 (DMTN, EPB49. DMT)

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Function

Structure

  • N-terminus is blocked
  • contains at least two actin-binding sites, one in the headpiece domain & one in the amino-terminal portion
  • consists of a large core fragment, the amino-terminal portion, & a small headpiece, the C-terminal portion
  • the headpiece can bind but cannot bundle actin filaments
  • belongs to the villin/gelsolin family
  • contains 1 HP domain (headpiece)

Compartment

Alternative splicing

named isoforms=3; long, short

Expression

More general terms

References

Database